About the GEPG

The goal of the Genome Engineering Production Group (GEPG) is to provide researchers with easy, low cost access to improved reagents for genome engineering. We gratefully acknowledge the HMS Tools and Technology program for start-up support.

The GEPG currently builds custom CRISPR sgRNA and TALE nuclease expression constructs. Users will provide gene names or target sequences, and the GEPG will handle design, production, sequence verification, and distribution of the resulting TALEN or CRISPR constructs. We can also provide consultation on engineering strategies and help with design of donor constructs.

In the near future, the GEPG plans to also offer CRISPR and TALE-based gene expression modifier tools, as well as an array of target site-specific donor vectors.

Direct links to order forms:
CRISPR sgRNA (or CRISPR & donor) Request Form
TALEN Request Form

March 2014:
We are now building custom donor constructs for knock-in approaches.

For more information please contact: gerald_marsischky@hms.harvard.edu or stephanie_mohr@hms.harvard.edu